Effect of β-alanine and the solvent composition on the solubility of solvate of calcium d-pantothenate containing four molecules of methanol and one molecule of water (D-PC·4MeOH·1H₂O)

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• 作者：Dandan Han ; Yumin Liu ; Xiaona Li ; Teng Zhang ; Zhenfang Li ; Shichao Du ; Mingxia Guo ; Shijie Xu ; Bo Yu ; Baohong Hou ; Junbo Gong ; ^{junbo_gong@tju.edu.cn}
• 关键词：Calcium d-pantothenate ; β-Alanine ; Solubility ; Polarity ; Salting-in effect
• 刊名：The Journal of Chemical Thermodynamics
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：106
• 期：Complete
• 页码：36-46
• 全文大小：1485 K
• 卷排序：106

文摘

The solubility of calcium d-pantothenate in water + methanol mixtures was measured by HPLC analysis method. The effect of β-alanine on the solubility of calcium d-pantothenate in a constant mole ratio of methanol and water was also determined by HPLC analysis method. The quaternary NRTL equation was first applied to correlating the quaternary solid-liquid equilibrium.