Regulation of a Spindle Positioning Factor at Kinetochores by SUMO-Targeted Ubiquitin Ligases

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Regulation of a Spindle Positioning Factor at Kinetochores by SUMO-Targeted Ubiquitin Ligases

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作者：Jö ; rg Schweiggert¹ ; ² ; ³ ; Lea Stevermann² ; ³ ; Davide Panigada¹ ; Daniel Kammerer² ; Dimitris Liakopoulos¹ ; ² ; ³ ; ^{dimitris.liakopoulos@crbm.cnrs.fr" class="auth_mail" title="E-mail the corresponding author}
刊名：Developmental Cell
出版年：2016
出版时间：22 February 2016
年：2016
卷：36
期：4
页码：415-427
全文大小：4643 K

文摘

•: Kar9 shuttles between cytoplasm and nucleus
•: STUbLs localize to kinetochores in a SUMO-dependent manner
•: STUbLs ubiquitylate Kar9 at kinetochores independently of Kar9 sumoylation
•: This process ensures spindle positioning and chromosome transmission fidelity

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