Chronic postnatal monoamine oxidase inhibition affects affiliative behavior in rat pupso

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• 作者：Sofia Blazevic ; Mirna Merkler ; Dora Persic ; Dubravka Hranilovic ; ^{dubravka@biol.pmf.hr}
• 关键词：5-HT ; 5-hydroxytryptamine (serotonin) ; DA ; dopamine ; NA ; noradrenaline ; USV ; ultrasonic vocalization ; MAO ; monoamine oxidase ; TCP ; tranylcypromine ; PND ; post-natal day ; ADR ; adrenaline ; LFC ; latency to first call ; TNC ; total number of calls ; ACD ; average call duration ; FME ; frequency of maximal energy
• 刊名：Pharmacology Biochemistry and Behavior
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：153
• 期：Complete
• 页码：60-68
• 全文大小：1203 K
• 卷排序：153

文摘

Chronic postnatal MAO inhibition with tranylcypromine raised cortical monoamine levels. Rat pups displayed stronger disturbance in 5-HT than in catecholamine homeostasis. Weight-gain, thermoregulation and affiliative behavior were diminished. Lower number of ultrasonic calls indicate reduced separation anxiety. Longer, lower pitched calls of variable waveforms suggest impaired acoustic communication.