Nedd8 targets ubiquitin ligase Smurf2 for neddylation and promote its degradation

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Nedd8 targets ubiquitin ligase Smurf2 for neddylation and promote its degradation

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作者：Jingyi Shu^a ; ^b ; ¹ ; Chao Liu^a ; ^b ; ¹ ; Rongfei Wei^b ; Ping Xie^c ; Shan He^b ; Lingqiang Zhang^b ; ^{zhanglq@nic.bmi.ac.cn" class="auth_mail" title="E-mail the corresponding author}
关键词：Protein neddylation ; Protein ubiquitination ; Nedd8 ; Ubiquitin ligase ; Smurf2
刊名：Biochemical and Biophysical Research Communications
出版年：2016
出版时间：20 May 2016
年：2016
卷：474
期：1
页码：51-56
全文大小：954 K

文摘

•: 10">Nedd8 promotes degradation of Smurf2.
•: 15">Smurf2 is substrate of neddylation.
•: Smurf2 neddylation promotes its ubiquitination.
•: Smurf2 is a potential neddylation E3.

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