Cris贸stomo Mart铆nez from Valencia was a pioneering microscopist in 17th-century Europe. The first microscopic representations
of skin in Spain appeared in an 18th-century work by Mart铆n Mart铆nez. Microbiology and histopathology progressed considerably in the late 19th century thanks to anatomists like Maestre de San Juan and surgeons like Federico Rubio Gal铆. The first
Spanish pathologist to specialize in dermatology was Antonio Mendoza, a colleague
of Jos茅 Eugenio de Olavide at the Hospital San Juan de Dios in Madrid. Claudio Sala and Juan de Az煤a also made significant contributions, including the description
of pseudoepithelioma.
Several disciples of Santiago Ram贸n y Cajal and Jorge FranciscoTello, such as Lorenzo Ruiz de Arcaute and Guillermo de la Rosa King, consolidated the dermatology laboratory, but the Civil War sent many into exile or deprived them of their professional status.
Juan Rubi贸 in Barcelona and Julio Rodr铆guez Puchol in Madrid were the immediate predecessors of today's dermatopathologists.
