Chromogranin A and other enteroendocrine markers in inflammatory bowel disease

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Chromogranin A and other enteroendocrine markers in inflammatory bowel disease

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作者：Sara Massironi^a ; ^{sara.massironi@policlinico.mi.it" class="auth_mail" title="E-mail the corresponding author} ; Alessandra Zilli^a ; ^b ; ^{alessandra.zilli86@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Federica Cavalcoli^a ; ^b ; ^{cavalcoli.federica@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Dario Conte^a ; ^b ; ^{dario.conte@unimi.it" class="auth_mail" title="E-mail the corresponding author} ; Maddalena Peracchi^a ; ^b ; ^{maddalena.peracchi@unimi.it" class="auth_mail" title="E-mail the corresponding author}
关键词：Chromogranin A ; Enteroendocrine cell ; Inflammatory bowel disease ; Crohn's disease ; Ulcerative colitis
刊名：Neuropeptides
出版年：2016
出版时间：August 2016
年：2016
卷：58
期：Complete
页码：127-134
全文大小：376 K

文摘

•: Enteroendocrine cell-derived peptides may control gastrointestinal inflammation.
•: Inflammatory processes may influence the neuroendocrine system by producing neuropeptides.
•: Raised CgA levels have been noted in 30% of IBD patients, mainly with active disease.
•: Changes in colonic production of other neuropeptides have been noted in IBD patients.
•: Enteroendocrine cells could become a novel therapeutic target for IBD patients.

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