Nicotinic α7 and α4β2 agonists enhance the formation and retrieval of recognition memory: Potential mechanisms for cognitive performance enhancement in neurological and psychiatric disorders

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Nicotinic α7 and α4β2 agonists enhance the formation and retrieval of recognition memory: Potential mechanisms for cognitive performance enhancement in neurological and psychiatric disorders

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作者：Samantha L. McLean^a ; Ben Grayson^b ; ^{b.grayson@manchester.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Samuel Marsh^b ; Samah H.O. Zarroug^c ; Michael K. Harte^b ; Jo C. Neill^b
关键词：Object recognition memory ; Female rat ; Delay-dependent deficits ; α7 Nicotinic receptors ; α4β2 Nicotinic receptors
刊名：Behavioural Brain Research
出版年：2016
出版时间：1 April 2016
年：2016
卷：302
期：Complete
页码：73-80
全文大小：941 K

文摘

•: Object recognition memory decays to 0 after a 6 h ITI in female hL rats.
•: Activation of nicotinic α7 and α4b2 receptors restores this memory.
•: Donepezil restores this memory while risperidone is ineffective.

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