Focal adhesion kinase is overexpressed in hepatocellular carcinoma and can be served as an independent prognostic factor

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• 作者：Fujii ; Tsutomu ; Koshikawa ; Katsumi ; Nomoto ; Shuji ; Okochi ; Osamu ; Kaneko ; Tetsuya ; Inoue ; Soichiro ; et. al.
• 关键词：Focal adhesion kinase ; Hepatocellular carcinoma ; Quantitative RT-PCR ; Prognostic factor
• 刊名：Journal of Hepatology
• 出版年：2004
• 出版时间：July, 2004
• 年：2004
• 卷：41
• 期：1
• 页码：104-111
• 全文大小：410 K

文摘

The development of human malignancies can be attributed to aberrant regulation of intracellular signal transduction pathways. In the current study, we aimed to evaluate focal adhesion kinase (FAK), a non-receptor tyrosine kinase, expression in hepatocellular carcinoma (HCC), and to explore the prognostic significance of FAK.