Emerging functional roles of cathepsin E

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• 作者：Nousheen Zaidi ; Clemens Hermann ; Timo Herrmann ; Hubert Kalbacher
• 关键词：Cathepsin E ; Aspartic protease
• 刊名：Biochemical and Biophysical Research Communications
• 出版年：2008
• 出版时间：12 December 2008
• 年：2008
• 卷：377
• 期：2
• 页码：327-330
• 全文大小：164 K

文摘

Cathepsin E is an intracellular aspartic protease of the endolysosomal pathway. It has been implicated in several physiological and pathological processes however, its exact functional role is yet to be elucidated. The present review gives an account of the major physiological functions that are associated to cathepsin E by various research groups and highlights the conditions developed in cathepsin E deficiency or the conditions where overexpression of cathepsin E is observed.