Morphological and genetic heterogeneity in multifocal lung adenocarcinoma: The case of a never-smoker woman

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Morphological and genetic heterogeneity in multifocal lung adenocarcinoma: The case of a never-smoker woman

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作者：Laura Bonanno^a ; ^{laura.bonanno@ioveneto.it" class="auth_mail" title="E-mail the corresponding author} ; ^{laura.bonanno@hotmail.it" class="auth_mail" title="E-mail the corresponding author} ; Fiorella Calabrese^b ; ^{fiorella.calabrese@unipd.it" class="auth_mail" title="E-mail the corresponding author} ; Giorgia Nardo^c ; ^{giorgia.nardo@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Daniele Calistri^d ; ^{daniele.calistri@irst.emr.it" class="auth_mail" title="E-mail the corresponding author} ; Michela Tebaldi^d ; ^{michela.tebaldi@irst.emr.it" class="auth_mail" title="E-mail the corresponding author} ; Gianluca Tedaldi^d ; ^{gianluca.tedaldi@irst.emr.it" class="auth_mail" title="E-mail the corresponding author} ; Valentina Polo^a ; ^e ; ^{valentina.polo@ioveneto.it" class="auth_mail" title="E-mail the corresponding author} ; Stefania Vuljan^b ; ^{stefvu@hotmail.it" class="auth_mail" title="E-mail the corresponding author} ; Adolfo Favaretto^a ; ^{adolfo.favaretto@ioveneto.it" class="auth_mail" title="E-mail the corresponding author} ; PierFranco Conte^a ; ^e ; ^{pierfranco.conte@unipd.it" class="auth_mail" title="E-mail the corresponding author} ; Alberto Amadori^a ; ^e ; ^{albido@unipd.it" class="auth_mail" title="E-mail the corresponding author} ; Federico Rea^f ; ^{federico.rea@unipd.it" class="auth_mail" title="E-mail the corresponding author} ; Stefano Indraccolo^c ; ^{stefano.indraccolo@unipd.it" class="auth_mail" title="E-mail the corresponding author}
关键词：NSCLCs ; non-small cell lung cancers ; NGS ; next generation sequencing ; CT ; computed tomography ; 18FDG-PET ; 18-Fluoro-d-glucose positron emission tomography ; PS ; performance status ; ECOG ; eastern cooperative oncology group
刊名：Lung Cancer
出版年：2016
出版时间：June 2016
年：2016
卷：96
期：Complete
页码：52-55
全文大小：768 K

文摘

•: Intra- and intertumor heterogeneity in patients with multiple lung adenocarcinomas.
•: Molecular profile may distinguish synchronous from methacronous lung carcinomas.
•: Molecular patterns may also identify subclonal genetic alterations in lung cancer.
•: Molecular findings may affect the treatment choice and the clinical outcome.