DAT1 gene polymorphism in alcoholism: a family-based association study

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• 作者：Franke ; Petra ; Schwab ; Sibylle G. ; Knapp ; Michael ; Gä ; nsicke ; Michael ; Delmo ; Cynthia ; et. al.
• 关键词：Alcoholism ; dopamine transporter (SLC6A3) ; family-based association study ; withdrawal ; seizure ; delirium
• 刊名：Biological Psychiatry
• 出版年：1999
• 出版时间：March 1, 1999
• 年：1999
• 卷：45
• 期：5
• 页码：652-654
• 全文大小：28.0 K

文摘

Background: The present study tests the hypothesis that the 9-repeat allele of the dopamine transporter gene (DAT1; SLC6A3) is more frequent in alcohol-dependent probands—and in particular those with severe withdrawal symptoms (seizures and/or delirium)—compared to nonalcoholics.