PYY-Dependent Restoration of Impaired Insulin and Glucagon Secretion in Type 2 Diabetes following Roux-En-Y Gastric Bypass Surgery

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PYY-Dependent Restoration of Impaired Insulin and Glucagon Secretion in Type 2 Diabetes following Roux-En-Y Gastric Bypass Surgery

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作者：Reshma D. Ramracheya¹ ; ^{reshma.ramracheya@ocdem.ox.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Laura J. McCulloch¹ ; Anne Clark¹ ; David Wiggins¹ ; Helene Johannessen² ; Magnus Kringstad Olsen² ; Xing Cai² ; Chun-Mei Zhao² ; Duan Chen² ; Patrik Rorsman¹ ; ³
刊名：Cell Reports
出版年：2016
出版时间：3 May 2016
年：2016
卷：15
期：5
页码：944-950
全文大小：1446 K

文摘

class="label">•: id="p0010">Roux-en-Y gastric bypass rapidly restores islet function and morphology in diabetic GK rats
class="label">•: id="p0015">The effects of RYGB on islet function are mediated by the gut hormone PYY and not GLP-1
class="label">•: id="p0020">In vitro PYY application to diabetic islets restores insulin and glucagon secretion

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