Succinic acid production by Actinobacillus succinogenes NJ113 using corn steep liquor powder as nitrogen source

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• 作者：Yong-lan Xi¹ ; Ke-quan Chen¹ ; Wen-yu Dai ; Jiang-feng Ma ; Min Zhang ; Min Jiang ; ^{bioengine@njut.edu.cn} ; Ping Wei ; Ping-Kai Ouyang
• 关键词：Corn steep liquor power ; Heme ; Nitrogen source ; Succinic acid ; Actinobacillus succinogenes
• 刊名：Bioresource Technology
• 出版年：2013
• 出版时间：May, 2013
• 年：2013
• 卷：136
• 期：Complete
• 页码：775-779
• 全文大小：295 K

文摘

In this study, corn steep liquor powder (CSL) was used as nitrogen source to replace the relatively costly yeast extract typically used for the production of succinic acid with Actinobacillus succinogenes NJ113. Moreover, when heme was added to the fermentation medium and the culture was agitated at a low speed, a maximum succinic acid concentration of 37.9 g/l was obtained from a glucose concentration of 50 g/l, and a productivity of 0.75 g/l/h was achieved. These yields are almost as high as for fermentation with glucose and yeast extract. These results suggest that heme-supplemented CSL may be a suitable alternative nitrogen source for a cost-effective method of producing succinic acid with A. succinogenes NJ113 while consuming less energy than previous methods.