p53R2 regulates thioredoxin reductase activity through interaction with TrxR2
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文摘
P53R2 binds to thioredoxin reductase 2 (TrxR2) in vivo and in vitro. P53R2 enhances TrxR activity. P53R2 regulates TrxR activity in a p53-independent manner. P53R2 acts as a positive regulator of TrxR2 activity under both normal and DNA damage conditions.
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