Paraneoplastic syndromes

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• 作者：Loretta Sweeney ; Theresa Howe
• 关键词：Neoplastic antibodies ; paraneoplastic endocrine syndromes ; paraneoplastic neurological syndromes ; paraneoplastic syndromes
• 刊名：Medicine
• 出版年：2016
• 出版时间：January 2016
• 年：2016
• 卷：44
• 期：1
• 页码：69-72
• 全文大小：87 K

文摘

Malignancy may uncommonly present with a paraneoplastic syndrome rather than as a direct result of the primary tumour or its metastases. Paraneoplastic syndromes are a heterogeneous group of syndromes that represent the non-metastatic systemic effects of malignant disease. Pathogenesis varies among syndromes but several humoral and immune mediators are implicated. Although some syndromes are rare, they can be very specific for an underlying malignant diagnosis. Recognition of the syndrome, treatment of the malignancy and supportive measures for the paraneoplastic syndrome may improve morbidity and mortality.