New 8-hydroxybriarane diterpenoids from the gorgonians Junceella juncea and Junceella fragilis (Ellisellidae)

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• 作者：Ping-Jyun Sung ; Chen-Hao Pai ; Yin-Di Su ; Tsong-Long Hwang ; Fu-Wen Kuo ; Tung-Yung Fan ; Jan-Jung Li
• 关键词：Junceella ; Junceol ; Fragilide ; Briarane ; Superoxide anion
• 刊名：Tetrahedron
• 出版年：2008
• 出版时间：5 May 2008
• 年：2008
• 卷：64
• 期：19
• 页码：4224-4232
• 全文大小：399 K

文摘

Four new 8-hydroxybriarane diterpenoids, including junceols A–C (1–3) and fragilide D (4), have been isolated from the gorgonian corals Junceella juncea and Junceella fragilis, respectively. The structures of briaranes 1–4 were elucidated by the interpretations of spectral data analysis. Briaranes 1–3 have displayed inhibitory effects on superoxide anion generation by human neutrophils.