Annexin A2 in primary afferents contributes to neuropathic pain associated with tissue type plasminogen activator

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Annexin A2 in primary afferents contributes to neuropathic pain associated with tissue type plasminogen activator

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作者：H. Yamanaka ; ^{yamanaka@hyo-med.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; K. Kobayashi ; M. Okubo ; K. Noguchi
关键词：ANX2 ; annexin A2 ; DRG ; dorsal root ganglia ; GAPDH ; glyceraldehyde 3-phosphate dehydrogenase ; IHC ; immunohistochemistry ; ir ; immunoreactivity ; ISH ; in situ hybridization ; LTP ; long-term potentiation ; PB ; phosphate buffer ; PBS ; phosphate-buffered saline ; SNI ; spared nerve injury ; tPA ; tissue-type plasminogen activator
刊名：Neuroscience
出版年：2016
出版时间：9 February 2016
年：2016
卷：314
期：Complete
页码：189-199
全文大小：4334 K

文摘

•: Peripheral nerve injury induced ANX2 and tPA in the primary afferent.
•: Administration of the inhibitor for ANX2–tPA complex suppressed neuropathic pain.
•: The role ANX2–tPA complex may be involved in the plastic changes in dorsal horn.

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