Persistent organic pollutants in early pregnancy and risk of gestational diabetes mellitus

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• 作者：Marina Vafeiadi^a ; ^bafom@uoc.gr ; Theano Roumeliotaki^a ; Georgia Chalkiadaki^a ; Panu Rantakokko^b ; Hannu Kiviranta^b ; Eleni Fthenou^a ; Soterios A. Kyrtopoulos^c ; Manolis Kogevinas^d ; ^e ; ^f ; Leda Chatzi^a
• 关键词：AhR ; aryl hydrocarbon receptor ; BMI ; body mass index ; BDE-47 ; tetra-bromodiphenyl ether ; CAR ; constitutive androstane receptor ; DDE ; dichlorodiphenyl dichloroethene ; DDT ; dichlorodiphenyl trichloroethane ; EDCs ; endocrine disrupting chemicals ; GDM ; gestational diabetes mellitus ; GWG ; gestational weight gain ; HCB ; hexachlorobenzene ; IOM ; Institute of Medicine ; LOQ ; limit of quantification ; PCBs ; polychlorinated biphenyls ; POPs ; persistent organic pollutants ; PXR ; pregnane X receptor ; SD ; standard
• 刊名：Environment International
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：98
• 期：Complete
• 页码：89-95
• 全文大小：295 K
• 卷排序：98

文摘

Exposure to environmental pollutants has been linked to type 2 diabetes. Environmental chemicals may be associated with glucose disorders during pregnancy. We explored effects of exposure to POPs on the development of gestational diabetes. Exposure to PCBs during pregnancy was associated with increased risk for GDM. DDE and HCB exposure was not significantly associated GDM risk.