Peroxisome proliferator-activated receptor δ improves porcine blastocyst hatching via the regulation of fatty acid oxidation

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• 作者：Jing Guo^a ; ¹ ; Wen-Fa Lu^b ; ¹ ; Shuang Liang^a ; Jeong-Woo Choi^a ; Nam-Hyung Kim^a ; ^{nhkim@chungbuk.ac.kr} ; Xiang-Shun Cui^a ; ^{xscui@chungbuk.ac.kr}
• 关键词：Embryonic development ; Pparδ ; Hatching ; ATP ; Fatty acid oxidation
• 刊名：Theriogenology
• 出版年：2017
• 出版时间：1 March 2017
• 年：2017
• 卷：90
• 期：Complete
• 页码：266-275
• 全文大小：1372 K
• 卷排序：90

文摘

Activation of PPARδ increased blastocyst hatching rate and blastocyst quality. The PPARδ can regulate the fatty acid oxidation resulting the increase of ATP production. Reactive oxygen species were modified and REDOX maintenance-related gene expression increased by the activation of PPARδ.