Crystalline keratopathy due to intravenous immunoglobulin in a 12-year-old girl with Kawasaki disease

详细信息    查看全文

• 作者：Vijay Viswanathan ; DNB ; DCH^a ; Prachi Agashe ; DNB^b ; Vandana Jain ; MD ; MBA^b ; Akshay Gopinathan Nair ; DNB^b ; ^c ; ^{akshaygn@gmail.com" class="auth_mail" title="E-mail the corresponding author}
• 刊名：Journal of American Association for Pediatric Ophthalmology and Strabismus
• 出版年：2016
• 出版时间：October 2016
• 年：2016
• 卷：20
• 期：5
• 页码：466-468.e1
• 全文大小：1230 K

文摘

Kawasaki disease (KD) is an acute, self-limiting, medium-vessel vasculitis that occurs predominantly in young children. The treatment of KD consists of intravenous immunoglobulin (IVIG) along with aspirin and, in IVIG-resistant cases, corticosteroids. Crystalline keratopathy with corneal deposition of the immunoglobulin is a rare complication of IVIG therapy. We report the case of a 12-year-old girl who received IVIG for KD and developed visual complaints, which were attributable to crystalline keratopathy and corneal edema. Cessation of IVIG and treatment with topical and systemic corticosteroids reversed the finding. At final follow-up, vision in both eyes was normal.