Acetylation mediates Cx43 reduction caused by electrical stimulation

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Acetylation mediates Cx43 reduction caused by electrical stimulation

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作者：Viviana Meraviglia^a ; ^b ; ¹ ; ² ; Valerio Azzimato^a ; ^c ; ¹ ; Claudia Colussi^d ; Maria Cristina Florio^b ; ² ; Anna Binda^e ; Alice Panariti^e ; Khaled Qanud^f ; Silvia Suffredini^b ; ² ; Laura Gennaccaro^b ; ^g ; ² ; Michele Miragoli^h ; ⁱ ; Andrea Barbuti^j ; Paul D. Lampe^k ; Carlo Gaetano^l ; Peter P. Pramstaller^b ; ² ; Maurizio C. Capogrossi^m ; Fabio A. Recchiaⁿ ; ^o ; Giulio Pompilio^a ; ^p ; Ilaria Rivolta^e ; Alessandra Rossini^b ; ² ; ^{alessandra.rossini@eurac.edu" class="auth_mail" title="E-mail the corresponding author}
关键词：GJ ; gap junctions ; Cx43 ; connexin43 ; HAT ; histone acetylase ; HDAC ; histone deacetylase ; CM ; cardiomyocyte ; NRCM ; neonatal rat cardiomyocyte ; hCStC ; human cardiac stromal cell
刊名：Journal of Molecular and Cellular Cardiology
出版年：2015
出版时间：October 2015
年：2015
卷：87
期：Complete
页码：54-64
全文大小：1795 K

文摘

•: Electrical activity modulates the acetylation/deacetylation balance of excitable cells.
•: Electrical activity modulates the acetylation status of Cx43.
•: Electrical activity modulates myocardial cell–cell communication through Cx43 acetylation.

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