Biochemical and genetic basis of orsellinic acid biosynthesis and prenylation in a stereaceous basidiomycete

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• 作者：Jana Braesel ; Janis Fricke ; Daniel Schwenk ; Dirk Hoffmeister ; ^{dirk.hoffmeister@leibniz-hki.de}
• 关键词：Orsellinic acid synthase ; Polyketide synthase ; Prenyltransferase ; Russulales ; Secondary metabolism ; Stereum
• 刊名：Fungal Genetics and Biology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：98
• 期：Complete
• 页码：12-19
• 全文大小：638 K
• 卷排序：98

文摘

A new prenylphenol natural product from a stereaceous basidiomycete was characterized. Two polyketide synthase genes were expressed in Aspergillus niger. Both synthases produced orsellinic acid. An orsellinic acid prenyltransferase was characterized in vitro.