The melting pot of the MHC II peptidome
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文摘

MHCII present antigens from a variety of intracellular and extracellular sources.

Endosomal and non-endosomal processing pathways contribute to the MHCII peptidome.

Lymphatic fluid is a rich source of pre-processed antigens for MHCII presentation.

Multiple processing pathways promote presentation of a broad repertoire of peptides.

Presentation of a broad peptide repertoire might be important for tolerance.

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