Multi-target therapeutics for neuropsychiatric and neurodegenerative disorders

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• 作者：Priya Bawa¹Author Vitae ; Priyamvada Pradeep¹Author Vitae ; Pradeep Kumar¹ ; Yahya E. Choonara¹ ; Girish Modi² ; ³ ; Viness Pillay¹ ; ³ ; ^{viness.pillay@wits.ac.za}Author Vitae
• 刊名：Drug Discovery Today
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：21
• 期：12
• 页码：1886-1914
• 全文大小：3072 K
• 卷排序：21

文摘

The polygenic nature of neuro-affected disorders favors multi-targeted drug design. Revisions of major diagnostic systems support DMLs for neuropsychiatric disorders. The difficulty titrating specific DML activities is an impediment to the approach.