Structural Basis of Pullulanase Membrane Binding and Secretion Revealed by X-Ray Crystallography, Molecular Dynamics and Biochemical Analysis

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Opening Hours
Collections
Help Via Email

Electronic Information Resources

Structural Basis of Pullulanase Membrane Binding and Secretion Revealed by X-Ray Crystallography, Molecular Dynamics and Biochemical Analysis

详细信息查看全文

作者：Alexandra East¹ ; ⁶ ; Ariel E. Mechaly² ; ⁶ ; ⁸ ; Gerard H.M. Huysmans³ ; Cé ; dric Bernarde³ ; Diana Tello-Manigne² ; Nathalie Nadeau³ ; Anthony P. Pugsley³ ; Alejandro Buschiazzo² ; ⁸ ; Pedro M. Alzari² ; Peter J. Bond¹ ; ⁴ ; ⁵ ; ⁷ ; ^{peterjb@bii.a-star.edu.sg" class="auth_mail" title="E-mail the corresponding author} ; Olivera Francetic³ ; ⁷ ; ^{ofrancet@pasteur.fr" class="auth_mail" title="E-mail the corresponding author}
关键词：pullulanase ; lipoprotein sorting ; type II secretion ; molecular dynamics ; X-ray crystallography ; liposomes ; POPE ; peripheral membrane proteins ; secretion signal
刊名：Structure
出版年：2016
出版时间：5 January 2016
年：2016
卷：24
期：1
页码：92-104
全文大小：5671 K

文摘

•: PulA lipoprotein was studied by molecular dynamics in a POPE membrane
•: MD analysis provided a detailed view of the lipoprotein Lol avoidance signal
•: PulA tether and N-terminal domains associate with membrane in silico and in vitro
•: Integrative analysis reveals a dynamic subdomain Ins essential for secretion

NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via email.