Overproduction of recombinant human bone morphogenetic protein-7 in Chinese hamster ovary cells

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Overproduction of recombinant human bone morphogenetic protein-7 in Chinese hamster ovary cells

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作者：Sena Yoon¹ ; Yujin Lee¹ ; Jia Pi ; Yongsu Jeong ; Kwangehee Baek ; Jaeseung Yoon ; ^{jsyoon@khu.ac.kr" class="auth_mail" title="E-mail the corresponding author}
关键词：Bone morphogenetic protein-7 (BMP-7) ; Chinese hamster ovary (CHO) cells ; Recombinant protein expression ; Stable cell line ; Bioreactor process
刊名：Protein Expression and Purification
出版年：2016
出版时间：April 2016
年：2016
卷：120
期：Complete
页码：87-91
全文大小：492 K

文摘

•: Established a stable CHO cell line expressing recombinant human BMP-7.
•: Established a pilot scale manufacturing process suitable for medical uses.
•: The purified rhBMP-7 was functionally active.

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