设为首页
收藏本站
网站地图
|
English
|
公务邮箱
About the library
Background
History
Leadership
Organization
Readers' Guide
Opening Hours
Collections
Help Via Email
Publications
Electronic Information Resources
LongR3 enhances Fc-fusion protein N-linked glycosylation while improving protein productivity in an industrial
CHO
cell
line
详细信息
查看全文
作者:
Yueming Qian
;
yueming.qian@bms.com
;
Amanda M. Lewis
;
Sarah M. Sidnam
;
Alison Bergeron
;
Ni
cho
las R. Abu-Absi
;
Nisha Vaidyanathan
;
Adam Deresienski
;
Nan-Xin Qian
;
Michael C. Borys
;
Zheng Jian Li
关键词:
Cell
culture
;
Chinese Hamster Ovary (
CHO
)
;
Glycosylation
;
PCR array
;
Protein production
;
Sialic acid
;
Neu2
刊名:Process Biochemistry
出版年:2017
出版时间:February 2017
年:2017
卷:53
期:Complete
页码:201-209
全文大小:2046 K
卷排序:53
文摘
Insulin-like growth factor analog LongR3 increases sialic acid content of Fc-fusion protein. LongR3 down-regulates sialidase gene expression. Decreased extra
cell
ular sialidase prevents
recombinant
glycoprotein desialylation.
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via
email
.