ALK-rearranged squamous cell lung carcinoma responding to crizotinib: A missing link in the field of non-small cell lung cancer?

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ALK-rearranged squamous cell lung carcinoma responding to crizotinib: A missing link in the field of non-small cell lung cancer?

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作者：Florence Vergne^a ; ^{florence.vergne@chu-brest.fr" class="auth_mail" title="E-mail the corresponding author} ; Gilles Qué ; ré ; ^a ; ^{gilles.quere@chu-brest.fr" class="auth_mail" title="E-mail the corresponding author} ; Sophie Andrieu-Key^b ; ^{sophie.andrieu@chu-brest.fr" class="auth_mail" title="E-mail the corresponding author} ; Renaud Descourt^a ; ^{renaud.descourt@chu-brest.fr" class="auth_mail" title="E-mail the corresponding author} ; Isabelle Quintin-Roué ; ^b ; ^{isabelle.quintin-roue@hu-brest.fr" class="auth_mail" title="E-mail the corresponding author} ; Matthieu Talagas^b ; ^c ; ^d ; ^{matthieu.talagas@chu-brest.fr" class="auth_mail" title="E-mail the corresponding author} ; Marc De Braekeleer^c ; ^e ; ^f ; ^{marc.debraekeleer@chu-brest.fr" class="auth_mail" title="E-mail the corresponding author} ; Pascale Marcorelles^b ; ^c ; ^d ; ^{pascale.marcorelles@chu-brest.fr" class="auth_mail" title="E-mail the corresponding author} ; Arnaud Uguen^b ; ^c ; ^f ; ^{arnaud.uguen@chu-brest.fr" class="auth_mail" title="E-mail the corresponding author} ; ^{arnaud.uguen@gmail.com" class="auth_mail" title="E-mail the corresponding author}
关键词：Lung cancer ; ALK ; Squamous cell carcinoma ; Crizotinib ; Immunohistochemistry
刊名：Lung Cancer
出版年：2016
出版时间：January 2016
年：2016
卷：91
期：Complete
页码：67-69
全文大小：1089 K

文摘

•: We report a rare case of ALK-rearranged lung squamous cell carcinoma with response to crizotinib therapy.
•: We highlight the challenges in the identification of this rare molecular subtype of lung cancer.
•: We point out the overlapping phenotypic criteria between ALK-rearranged squamous cell carcinomas and adenocarcinomas.

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