Anatomic Versus Physiologic Assessment of Coronary Artery Disease: Role of Coronary Flow Reserve, Fractional Flow Reserve, and Positron Emission Tomography Imaging in Revascularization Decision-Making

详细信息    查看全文

• 作者：K. Lance Gould ; Nils P. Johnson ; Timothy M. Bateman ; Rob S. Beanl ; s ; Frank M. Bengel ; Robert Bober ; Paolo G. Camici ; Manuel D. Cerqueira ; Benjamin J.W. Chow ; Marcelo F. Di Carli ; Sharmila Dorbala ; Henry Gewirtz ; Robert J. Gropler ; Philipp A. Kaufmann ; Paul Knaapen ; Juhani Knuuti ; Michael E. Merhige ; K. Peter Rentrop ; Terrence D. Ruddy ; Heinrich R. Schelbert ; et al.
• 关键词：coronary flow ; coronary physiology ; ischemia ; PET perfusion imaging ; revascularization
• 刊名：Journal of the American College of Cardiology
• 出版年：29 October, 2013
• 年：2013
• 卷：62
• 期：18
• 页码：1639-1653
• 全文大小：2718 K

文摘

Angiographic severity of coronary artery stenosis has historically been the primary guide to revascularization or medical management of coronary artery disease. However, physiologic severity defined by coronary pressure and/or flow has resurged into clinical prominence as a potential, fundamental change from anatomically to physiologically guided management. This review addresses clinical coronary physiology鈥攑ressure and flow鈥攁s clinical tools for treating patients. We clarify the basic concepts that hold true for whatever technology measures coronary physiology directly and reliably, here focusing on positron emission tomography and its interplay with intracoronary measurements.