Next generation functional proteomics in non-model plants: A survey on techniques and applications for the analysis of protein complexes and post-translational modifications

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• 作者：Noor Remmerie^a ; ^b ; ¹ ; Thomas De Vijlder^a ; ^b ; ¹ ; Kris Laukens^a ; ^c ; Thanh Hai Dang^c ; Filip Lemiè ; re^a ; ^d ; Inge Mertens^e ; Dirk Valkenborg^e ; ^f ; Ronny Blust^g ; Erwin Witters^a ; ^e ; ^g ; ^{Erwin.witters@vito.be"" rel=""nofollow} [Author vitae]
• 关键词：Cross-species ; Protein– ; protein interactions ; Post translational modifications ; Computational methods
• 刊名：Phytochemistry
• 出版年：2011
• 出版时间：July 2011
• 年：2011
• 卷：72
• 期：10
• 页码：1192-1218
• 全文大小：771 K

文摘

The congruent development of computational technology, bioinformatics and analytical instrumentation makes proteomics ready for the next leap. Present-day state of the art proteomics grew from a descriptive method towards a full stake holder in systems biology. High throughput and genome wide studies are now made at the functional level. These include quantitative aspects, functional aspects with respect to protein interactions as well as post translational modifications and advanced computational methods that aid in predicting protein function and mapping these functionalities across the species border. In this review an overview is given of the current status of these aspects in plant studies with special attention to non-genomic model plants.