Metabolism of Free Guanidine in Bacteria Is Regulated by a Widespread Riboswitch Class

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• 作者：James W. Nelson¹ ; ⁶ ; Ruben M. Atilho² ; ⁶ ; Madeline E. Sherlock² ; ⁶ ; Randy B. Stockbridge³ ; ⁴ ; Ronald R. Breaker¹ ; ² ; ⁵ ; ⁷ ; ⁸ ; ^{ronald.breaker@yale.edu}
• 关键词：aptamer ; EmrE ; multidrug efflux ; noncoding RNA ; orphan riboswitch ; SugE ; urea carboxylase ; ykkC
• 刊名：Molecular Cell
• 出版年：2017
• 出版时间：19 January 2017
• 年：2017
• 卷：65
• 期：2
• 页码：220-230
• 全文大小：2006 K
• 卷排序：65

文摘

Bacteria naturally produce, sense, and respond to guanidine Most ykkC RNA motif representatives are aptamer domains of guanidine riboswitches Riboswitches control guanidine carboxylase genes previously declared urea carboxylases Many annotated EmrE and SugE multidrug efflux pumps are likely guanidine transporters