Management of familial heterozygous hypercholesterolemia: Position Paper of the Polish Lipid Expert Forum

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• 作者：Andrzej Rynkiewicz ; MD ; PhD^a ; Barbara Cybulska ; MD ; PhD^e ; Maciej Banach ; MD ; PhD^f ; ^{maciejbanach@aol.co.uk} ; Krzysztof Filipiak ; MD ; PhD^g ; Tomasz Guzik ; MD ; PhD^j ; Barbara Idzior-Walu? ; MD ; PhD^k ; Jacek Imiela ; MD ; PhD^m ; Piotr Jankowski ; MD ; PhD^l ; Longina K?osiewicz-Latoszek ; MD ; PhD^e ; ⁱ ; Janusz Limon ; MD ; PhD^b ; Ma?gorzata My?liwiec ; MD ; PhD^c ; Grzegorz Opolski ; MD ; PhD^h ; Andrzej Steciwko ; MD ; PhDⁿ ; Janina St?pi¨½ska ; MD ; PhD^o ; Tomasz Zdrojewski ; MD ; PhD^d
• 关键词：Diagnosis ; Familial hypercholesterolemia ; Heterozygous familial hypercholesterolemia ; Prevention ; Therapy
• 刊名：Journal of Clinical Lipidology
• 出版年：2013
• 出版时间：May-June, 2013
• 年：2013
• 卷：7
• 期：3
• 页码：217-221
• 全文大小：125 K

文摘

Heterozygous familial hypercholesterolemia (HFH) affects on average 1 in 500 individuals in European countries, and it is estimated that HeFH in Poland may affect more than 80,000 people. Cardiovascular mortality in individuals with FH between 20 and 39 years of age is 100 times higher than in the general population. HFH is a relatively common lipid disorder, but usually still remaining undiagnosed and untreated. A very high risk of cardiovascular diseases and a shortened lifespan in patients with this condition require early diagnosis and intensive treatment. The aim of the position paper was to present the importance and scale of this problem in Poland, which has not been raised enough so far, as well as the recommendations of diagnosis, treatment and prevention methods.