Three ferritin subunit analogs in Chinese giant salamander (Andrias davidianus) and their response to microbial stimulation

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Three ferritin subunit analogs in Chinese giant salamander (Andrias davidianus) and their response to microbial stimulation

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作者：Xiuling You^a ; Jianghong Sheng^a ; Liu Liu^a ; Dongsong Nie^b ; Zhiyong Liao^a ; ^{zyliap@163.com" class="auth_mail" title="E-mail the corresponding author}
关键词：Chinese giant salamander ; Ferritin ; cDNA cloning ; Immune response
刊名：Molecular Immunology
出版年：2015
出版时间：October 2015
年：2015
卷：67
期：2
页码：642-651
全文大小：3206 K

文摘

•: Three cDNAs of ferritin H chain, L chain, and M chain were identified from Chinese giant salamander.
•: cgsFer expression responded to Andrias davidianus ranavirus infection and LPS stimulation.
•: Iron challenge regulated cgsFers expression via the IRE in the 5′-UTR.
•: Recombinant cgsFers showed significant iron binding and ferroxidase activity, and microbiostatic effect as well.

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