Protective immunity of a Pichia pastoris expressed recombinant iridovirus major capsid protein in the Chinese giant salamander, Andrias davidianus

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Protective immunity of a Pichia pastoris expressed recombinant iridovirus major capsid protein in the Chinese giant salamander, Andrias davidianus

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作者：Yong Zhou^a ; ^b ; Yuding Fan^a ; Scott E. LaPatra^c ; Jie Ma^a ; Jin Xu^a ; Yan Meng^a ; Nan Jiang^a ; Lingbing Zeng^a ; ^{zlb@yfi.ac.cn" class="auth_mail" title="E-mail the corresponding author}
关键词：Chinese giant salamander ; Iridovirus ; MCP ; Pichia pastoris expression ; Protective immunity
刊名：Vaccine
出版年：2015
出版时间：13 October 2015
年：2015
卷：33
期：42
页码：5662-5669
全文大小：1143 K

文摘

•: The GSIV MCP was expressed in Pichia pastoris by optimization of the MCP codons.
•: The purified O-MCP could self-assemble into virus-like particles.
•: The O-MCP stimulated a protective immune response in the Chinese giant salamander.

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