We studied 417 DLB patients and 1790 controls in our primary analysis.

7 pathogenic LRRK2 variants and 18 common LRRK2 variants were assessed.

We identified 1 DLB patient who was a carrier of the LRRK2 p.G2019S mutation.

The p.N551K-R1398H-K1423K haplotype showed a non-significant trend toward a protective association with DLB risk.

These findings suggest that LRRK2 variation may play a limited role in susceptibility to DLB.