Differential fMRI BOLD responses in amygdala in intermittent explosive disorder as a function of past Alcohol Use Disorder

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Differential fMRI BOLD responses in amygdala in intermittent explosive disorder as a function of past Alcohol Use Disorder

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作者：Emil F. Coccaro^a ; ^{ecoccaro@bsd.uchicago.edu" class="auth_mail" title="E-mail the corresponding author} ; Sarah K. Keedy^a ; Stephanie M. Gorka^b ; Andrea C. King^a ; Jennifer R. Fanning^a ; Royce J. Lee^a ; K. Luan Phan^b ; ^c
关键词：Intermittent explosive disorder ; Alcohol Use Disorder ; Aggression ; FMRI ; Amygdala ; Emotional information processing
刊名：Psychiatry Research: Neuroimaging
出版年：2016
出版时间：30 November 2016
年：2016
卷：257
期：Complete
页码：5-10
全文大小：335 K

文摘

•: IED is associated with hyperactivation of the amygdala in response to anger faces.
•: Previous studies suggest that alcoholism dampens amygdala AMYG responses to emotional stimuli.
•: In this study, IED subjects with history of alcoholism had a blunted amygdala response to anger faces.
•: Thus, history of alcoholism should be considered in the interpretation of emotional related fMRI studies.

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