On-column trypsin digestion coupled with LC-MS/MS for quantification of apolipoproteins
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文摘

Simultaneous absolute quantification of 8 apolipoproteins associated with high and low density lipoproteins (HDL and LDL).

High throughput on-line coupling of immobilized trypsin digestion with quantitative LC-MS/MS analysis.

Correlations between consensus structures of apolipoproteins and pattern of fast trypsin releasable target peptides.

Comparison of on-line and off-line batch digestions of apoA-I and apoB-100.

Multivariate regression analysis used to assess correlations between lipid and apolipoprotein concentrations in patient sera.

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