Serum metabolomics in rats models of ketamine abuse by gas chromatography-mass spectrometry

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Serum metabolomics in rats models of ketamine abuse by gas chromatography-mass spectrometry

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作者：Meiling Zhang^a ; Congcong Wen^a ; Yuan Zhang^a ; Fa Sun^a ; Shuanghu Wang^b ; Jianshe Ma^a ; Kezhi Lin^a ; Xianqin Wang^a ; Guanyang Lin^c ; ^{guanyanglinwzmc@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Lufeng Hu^c ; ^{hulufeng79@sina.com" class="auth_mail" title="E-mail the corresponding author}
关键词：Serum ; Metabolomics ; GC/MS ; Ketamine ; Abuse
刊名：Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences
出版年：2015
出版时间：1 December 2015
年：2015
卷：1006
期：Complete
页码：99-103
全文大小：986 K

文摘

•: This study examines the change in serum metabolites after ketamine abuse.
•: We observed lipid metabolism, energy metabolism and amino metabolism are disorder after ketamine abuse.
•: This study may aid the understanding of the ketamine abuse mechanism.
•: This study offer invaluable information for the therapy treatment of ketamine abuse.

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