Early Development of Definitive Erythroblasts from Human Pluripotent Stem Cells Defined by Expression of Glycophorin A/CD235a, CD34, and CD36

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Early Development of Definitive Erythroblasts from Human Pluripotent Stem Cells Defined by Expression of Glycophorin A/CD235a, CD34, and CD36

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作者：Bin Mao¹ ; Shu Huang¹ ; Xulin Lu¹ ; Wencui Sun¹ ; Ya Zhou¹ ; Xu Pan¹ ; Jinfeng Yu¹ ; Mowen Lai¹ ; Bo Chen¹ ; Qiongxiu Zhou¹ ; Song Mao³ ; Guohui Bian¹ ; Jiaxi Zhou² ; Tatsutoshi Nakahata⁴ ; Feng Ma¹ ; ² ; ⁵ ; ^{mafeng@hotmail.co.jp" class="auth_mail" title="E-mail the corresponding author}
关键词：hESC ; hiPSC ; hematopoiesis ; development ; erythroblasts ; erythropoiesis ; endothelial cells ; GPA ; CD36 ; CD34
刊名：Stem Cell Reports
出版年：2016
出版时间：8 November 2016
年：2016
卷：7
期：5
页码：869-883
全文大小：4493 K

文摘

•: The hPSC/AGM-S3 co-culture system generates considerable definitive erythroblasts
•: hPSC-derived erythroblasts initiate from a unique GPA⁺CD34^lowCD36⁻ fraction
•: Human early erythropoiesis can be traced by serial expression of CD34, GPA, and CD36

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