Effects of norepinephrine on spontaneous firing activity of cerebellar Purkinje cells in vivo in mice

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Effects of norepinephrine on spontaneous firing activity of cerebellar Purkinje cells in vivo in mice

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作者：Ao Guo^a ; ^b ; ¹ ; Jun-Yang Feng^a ; ^b ; ¹ ; Jia Li^a ; ^b ; ¹ ; Nan Ding^a ; ^b ; Ying-Jun Li^a ; ^b ; De-Lai Qiu^a ; ^b ; Ri-Long Piao^b ; ^{piaorl@ybu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Chun-Ping Chu^a ; ^b ; ^{cpchu@ybu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; ^{chpchu@hotmail.com" class="auth_mail" title="E-mail the corresponding author}
关键词：Norepinephrine ; Purkinje cell ; Molecular layer interneuron ; Spontaneous activity ; GABAA receptor ; AMPA receptor
刊名：Neuroscience Letters
出版年：2016
出版时间：26 August 2016
年：2016
卷：629
期：Complete
页码：262-266
全文大小：1230 K

文摘

•: NE decreased spontaneous SS firing rate of PCs and increased spontaneous firing of MLIs.
•: Blocking GABA_A receptors activity revealed the NE-induced increase in SS firing of PCs.
•: Blocking AMPA receptors enhanced the NE-induced inhibition in SS firing of PCs.

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