Preserved Capacity for Placebo Analgesia in the Elderly

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• 作者：Nathalie Wrobel^&lowast ; ; ^&dagger ; ; ^{nathalie.wrobel@ki.se} ; Tahmine Fadai^&Dagger ; ; Stefanie Brassen^§ ; ; Ulrike Bingel^&dagger ;
• 关键词：Lifespan ; placebo analgesia ; placebo effect ; experimental pain ; elderly ; adults ; endogenous pain modulation ; learning ; expectation
• 刊名：The Journal of Pain
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：17
• 期：12
• 页码：1318-1324
• 全文大小：526 K
• 卷排序：17

文摘

Prevalence of chronic pain rises with age. Age-related changes in the descending modulatory pathways could be a possible mechanism. We experimentally explored endogenous pain modulation in younger compared with older adults. Older adults show preserved capacity for endogenous pain modulation. In the future, nonpharmacological analgesic treatment strategies could be enhanced in the elderly.