Renoprotective effect of DPP-4 inhibitors against free fatty acid-bound albumin-induced renal proximal tubular cell injury

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Opening Hours
Collections
Help Via Email

Electronic Information Resources

Renoprotective effect of DPP-4 inhibitors against free fatty acid-bound albumin-induced renal proximal tubular cell injury

详细信息查看全文

作者：Yuki Tanaka^a ; Shinji Kume^a ; ^{skume@belle.shiga-med.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Masami Chin-Kanasaki^a ; Hisazumi Araki^a ; Shin-ichi Araki^a ; Satoshi Ugi^a ; Takeshi Sugaya^b ; Takashi Uzu^a ; Hiroshi Maegawa^a
关键词：Diabetic nephropathy ; DPP&ndash ; 4 inhibitors ; Free fatty acid ; Albuminuria ; Proximal tubular cell
刊名：Biochemical and Biophysical Research Communications
出版年：2016
出版时间：12 February 2016
年：2016
卷：470
期：3
页码：539-545
全文大小：1369 K

文摘

•: DPP4 inhibitors show a direct renoprotective effect against lipotoxicity.
•: DPP4 inhibitors inhibit lipotoxicity-mediated inflammation in renal tubular cells.
•: DPP4 inhibitors inhibit lipotoxicity-mediated fibrosis in renal tubular cells.
•: DPP4 inhibitors renal tubular cells against lipotoxicity-mediated apoptosis.
•: Linagliptin, a DPP4 inhibitor, improved lipotoxicity-induced kidney damage in mice.

NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via email.