Effect of carbamazepine on the sleep microstructure of temporal lobe epilepsy patients: a cyclic alternating pattern-based study

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• 作者：Chetan S. Nayak^a ; ^c ; Sanjib Sinha^a ; ^{sanjib_sinha2004@yahoo.co.in} ; Madhu Nagappa^a ; Kandavel Thennarasu^b ; Arun B. Taly^a
• 关键词：Arousal ; CAP ; Sleep microstructure ; Temporal lobe epilepsy
• 刊名：Sleep Medicine
• 出版年：2016
• 出版时间：November-December 2016
• 年：2016
• 卷：27-28
• 期：Complete
• 页码：80-85
• 全文大小：263 K
• 卷排序：27

文摘

Sleep microstructure was assessed in drug naïve and carbamazepine (CBZ) treated patients with temporal lobe epilepsy (TLE). Assessment of cyclic alternating pattern (CAP) and arousal parameters was carried out. Patients with TLE showed greater sleep microstructural disturbances compared to healthy controls. Microstructural disturbances were worse in CBZ treated patients compared to drug naïve during non-rapid eye movement sleep.