Mitochondrial H<sub>2</sub>O<sub>2</sub> in Lung Antigen-Presenting Cells Blocks NF-κB Activation to Prevent Unwarranted Immune Activation

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Opening Hours
Collections
Help Via Email

Electronic Information Resources

Mitochondrial H₂O₂ in Lung Antigen-Presenting Cells Blocks NF-κB Activation to Prevent Unwarranted Immune Activation

详细信息查看全文

作者：Anupriya Khare¹ ; ⁸ ; Mahesh Raundhal¹ ; ⁸ ; Krishnendu Chakraborty¹ ; ⁸ ; Sudipta Das¹ ; Catherine Corey² ; Christelle K. Kamga² ; Kelly Quesnelle³ ; Claudette St. Croix⁴ ; Simon C. Watkins⁴ ; Christina Morse¹ ; Timothy B. Oriss¹ ; Rachael Huff¹ ; Rachel Hannum¹ ; Prabir Ray¹ ; ⁵ ; Sruti Shiva² ; ⁶ ; ⁷ ; Anuradha Ray¹ ; ⁵ ; ^{raya@pitt.edu" class="auth_mail" title="E-mail the corresponding author}
刊名：Cell Reports
出版年：2016
出版时间：24 May 2016
年：2016
卷：15
期：8
页码：1700-1714
全文大小：3989 K

文摘

•: Immune tolerance invokes PPARγ-dependent mitochondrial H₂O₂ in lung immune cells
•: PPARγ promotes superoxidase dismutase expression, which is central to H₂O₂ generation
•: PPARγ-dependent mitochondrial H₂O₂ inhibits NF-κB activation to suppress inflammation
•: PPARγ links the nucleus, mitochondria, and cell cytoplasm to ensure immune quiescence

NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via email.