A multiscale approach for fluid interfaces covered with large molecules is presented.

At the nanoscale, coarse-grained molecular dynamics simulates the molecular fluids.

Tension and elasticity of the interface is computed at the nanoscale.

They are used at the macroscale in a level-set/ghost-fluid/immersed-boundary method.

Simulation of deflating asphaltene-covered drops match crumpling seen experimentally.