The first synthesis of Crucigasterin 277—a polyunsaturated C-18 amino alcohol from the Mediterranean tunicate Pseudomonas crucigaster

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The first synthesis of Crucigasterin 277—a polyunsaturated C-18 amino alcohol from the Mediterranean tunicate Pseudomonas crucigaster

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作者：Solveig Flock^a ; ^b ; Simen Antonsen^a ; Harrison Gallantree-Smith^a ; Anne Marie Langseter^a ; Lars Skattebø ; l^b ; Yngve Stenstrø ; m^a ; ^{yngve.stenstrom@nmbu.no" class="auth_mail" title="E-mail the corresponding author}
关键词：Crucigasterin 277 ; C-18 aminoalcohol ; Polyunsaturated fatty acid ; EPA ; Iodolactonization ; Marine tunicate metabolite
刊名：Tetrahedron
出版年：2016
出版时间：28 July 2016
年：2016
卷：72
期：30
页码：4518-4522
全文大小：342 K

文摘

Starting from eicosapentaenoic acid (EPA) and d-alanine, the first synthesis of (2R, 3S)-crucigasterin 277, a polyunsaturated C-18 amino alcohol from the Mediterranean tunicate, Pseudodistoma crucigaster, is described.