Detection of genetic diversity and selection at the coding region of the melanocortin receptor 1 (MC1R) gene in Tibetan pigs and Landrace pigs

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Opening Hours
Collections
Help Via Email

Electronic Information Resources

Detection of genetic diversity and selection at the coding region of the melanocortin receptor 1 (MC1R) gene in Tibetan pigs and Landrace pigs

详细信息查看全文

作者：Rui Liu^a ; ^b ; ¹ ; Long Jin^a ; ^b ; ¹ ; Keren Long^a ; ^b ; Jie Chai^a ; ^b ; Jideng Ma^a ; ^b ; Qianzi Tang^a ; ^b ; Shilin Tian^a ; ^b ; ^c ; Yaodong Hu^a ; ^b ; Ling Lin^c ; Xun Wang^a ; ^b ; Anan Jiang^a ; ^b ; Xuewei Li^a ; ^b ; ^{lixuewei9125@126.com" class="auth_mail" title="E-mail the corresponding author} ; Mingzhou Li^a ; ^b ; ^{mingzhou.li@sicau.edu.cn" class="auth_mail" title="E-mail the corresponding author}
关键词：MC1R ; melanocortin 1 receptor ; E ; Extension ; ASIP ; agouti signaling protein ; TYRP1 ; tyrosinase related protein 1 ; EDNRB ; endothelin receptor beta ; KITLG ; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog ; OCA2 ; oculocutaneous albinism II ; CDS ; coding region sequence ; PCR ; polymerase chain reaction ; SNP ; single nucleotide polymorphism ; dN ; the relative frequencies of non-synonymous ; dS ; the relative frequencies of synonymous
刊名：Gene
出版年：2016
出版时间：10 January 2016
年：2016
卷：575
期：2
页码：537-542
全文大小：441 K

文摘

•: Genetic variability at the MC1R is lower in European white Landrace pigs than in Asian black Tibetan pigs.
•: Tibetan pigs possessed shared haplotypes, suggesting a possibility of recent introgression event.
•: We detected positive selection at the MC1R in both Tibetan pigs and Landrace pigs through the dN /dS analysis.
•: Eurasian wild boars may have initially experienced different selection and MC1R alleles diversified in modern domestication.

NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via email.