Inhibition of local effects induced by Bothrops erythromelas snake venom: Assessment of the effectiveness of Brazilian polyvalent bothropic antivenom and aqueous leaf extract of Jatropha gossypiifolia

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• 作者：Juliana Fé ; lix-Silva^a ; Jacyra A.S. Gomes^a ; Jacinthia B. Xavier-Santos^a ; Jú ; lia G.R. Passos^a ; Arnó ; bio A. Silva-Junior^a ; Denise V. Tambourgi^b ; Matheus F. Fernandes-Pedrosa^a ; ^{mpedrosa@ufrnet.br}
• 关键词：Bothrops erythromelas ; Caatinga's lancehead ; Jatropha gossypiifolia ; Antiophidic activity ; Bothropic antivenom
• 刊名：Toxicon
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：125
• 期：Complete
• 页码：74-83
• 全文大小：1086 K
• 卷排序：125

文摘

Despite immunological cross-reactivity with BeV, BAv was poorly active against local and enzymatic activities of this venom. AE inhibited efficiently local effects and enzymatic activities induced by BeV. This study demonstrates the significant potential of this medicinal plant as a promising adjuvant in antivenom therapy.