Genetic Adaptation to Diet Preserves Longevity

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• 作者：Albertha聽J.M. Walhout
• 刊名：Cell Metabolism
• 出版年：4 February, 2014
• 年：2014
• 卷：19
• 期：2
• 页码：177-178
• 全文大小：109 K

文摘

Diet affects cellular metabolism and organismal life history traits. use Caenorhabditis elegans and its bacterial diets to unveil genetic perturbations in proline catabolism that shorten lifespan, but, only on specific Escherichia coli diets, thereby unveiling a genome-encoded adaptive response to different nutritional states.