Label-free electrochemical aptasensor for adenosine detection based on cascade signal amplification strategy

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• 作者：Jing Shen ; Hongyang Wang ; Chunxiang Li ; ^{lichunxiang76@126.com} ; Yanyan Zhao ; Xijuan Yu ; Xiliang Luo ; ^{xiliangluo@qust.edu.cn}
• 关键词：Electrochemical sensor ; Aptamer ; Adenosine detection ; Strand-replacement DNA polymerization ; RCA
• 刊名：Biosensors and Bioelectronics
• 出版年：2017
• 出版时间：15 April 2017
• 年：2017
• 卷：90
• 期：Complete
• 页码：356-362
• 全文大小：597 K
• 卷排序：90

文摘

A sensitive and selective label-free aptasensor for adenosine was developed. Strand-replacement DNA polymerization and RCA for dual-amplification was designed. An impressive detection limit of 0.032 nM toward adenosine could be achieved.